In vitro synergism of FR-31564, a new phosphonic acid antibiotic.
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منابع مشابه
In vitro synergism of FR-31564, a new phosphonic acid antibiotic.
Against most test strains of Gram-negative bacilli, the in vitro effect of FR-31564 together with beta-lactam antibiotics or trimethoprim was strongly synergistic; with tetracycline and nalidixic acid the effect was additive; and with gentamicin and sulfamethoxazole the effect was additive or antagonistic. FR-31564 was markedly synergistic with beta-lactam antibiotics against beta-lactam antibi...
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Fosmidomycin (FR-31564), a phosphonic acid derivative, was combined with cefazolin, cephalexin, ampicillin, carbenicillin, ticarcillin, gentamicin, and trimethoprim. Synergy between fosmidomycin and penicillins or cephalosporins was found for 37 to 52% of the Enterobacteriaceae tested. Synergy with trimethoprim was found against 55% of bacteria isolated, but only 17% of the strains showed syner...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1981
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.34.876